Luck passed for 334 yards last Sunday against the New England Patriots, but he threw three interceptions in a 59-24 loss. In the Colts' four losses, Luck has five touchdown passes and nine interceptions. In their wins, he has seven touchdowns and three interceptions.
Things could improve for the rookie Sunday against the Bills. Buffalo ranks 27th in the league in total defense, allowing 387.4 yards per game.
Luck also has been a standout at home. He's thrown eight touchdown passes and two interceptions at Lucas Oil Stadium, where the Colts are 4-1. Indianapolis (6-4) needs a win to solidify its spot in the playoff hunt.
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