Colts coach Chuck Pagano says outside linebacker Dwight Freeney will not play Sunday against Minnesota, and receiver Austin Collie is doubtful.
Freeney has not practiced since spraining his left ankle in last weekend's loss at Chicago. Pagano would not say if it was a high ankle sprain.
Collie has not played since sustaining a concussion Aug. 19 against Pittsburgh. Collie was cleared to practice last week and again Tuesday. But after working out Wednesday, Pagano says Collie suffered a setback.
Linebacker Pat Angerer (fractured foot) and offensive guard Joe Reitz (knee) also have been ruled out of the Colts' home opener.
Receiver T.Y. Hilton (shoulder) is listed as probable. Right tackle Winston Justice (concussion) has practiced this week, but is listed as questionable.
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