Natalie Novosel scored 16 points and Notre Dame advanced to the Raleigh Regional final by routing St. Bonaventure 79-35 on Sunday in the semifinals.
Kalia Turner scored 14 points and Kayla McBride added 10 for the top-seeded Irish (33-3).
They shot 52.5 percent, never trailed and led by 45 before matching a 22-year-old record for scoring margin in the regional round while cruising into the finals for the second straight year.
Notre Dame will play second-seeded Maryland (31-4) on Tuesday night with a spot in the Final Four on the line.
CeCe Dixon had 13 points and Doris Ortega added 11 for the fifth-seeded Bonnies (31-4).
They shot a season-low 19 percent, allowed a season-high point total and finished with a season-worst 21 turnovers. Leading scorer Jessica Jenkins was scoreless - she entered averaging 14 points - and missed all six of her shots.
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